organic compounds
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The asymmetric unit of the title compound, C11H10ClN3O, contains two geometrically different molecules, A and B, in both of which the pyridazine rings are essentially planar with r.m.s. deviations of 0.0137 and 0.0056Å, respectively. In molecule A, the dihedral angle between the pyridazine and benzene rings is 6.5 (2)°, whereas in molecule B it is 27.93 (7)°. In molecule B, an intramolecular N—HO hydrogen bond forms an S(5) ring motif. In both molecules, S(6) ring motifs are present due to non-classical C—HN hydrogen bonds. The π–π interactions between the pyridazine rings of A molecules [3.4740 (13) Å] and B molecules [3.4786 (17) Å] have very similar centroid–centroid separations. π–π Interactions also occur between the benzene rings of B molecules with a centroid–centroid separation of 3.676 (2) Å and a slippage of 1.02 Å. In the crystal, the molecules are linked into chains extending along [010] by C—HN and C—HCl interactions.
organic compounds
Open access
In the title compound, C17H18N2O3S, the dihedral angles between the thiophene ring and the ethyl ester group and the pyridine-4-carboxamide unit are 7.1 (2) and 9.47 (11)°, respectively. An intramolecular N—HO hydrogen bond generates an S(6) ring. In the crystal, inversion dimers linked by pairs of C—HO hydrogen bonds between the tetrahydro-1-benzothiophene and the pyridine-4-carboxamide residues generate R22(16) loops. There exists positional disorder in three methelene groups of the cyclohexane ring and the terminal C atom of the ethyl ester side chain in a 0.691 (14):0.309 (14) occupancy ratio.
organic compounds
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In the title compound, C13H17NO3S, the dihedral angles between the thiophene ring and the ethyl ester and acetamide groups are 5.21 (13) and 10.06 (16)°, respectively. The cyclohezene ring adopts a half-chair conformation. An S(6) ring is formed due to an intramolecular N—HO hydrogen bond. In the crystal, molecules are linked by C—HO interactions between the tetrahydro-1-benzothiophene unit and the ethyl ester group, forming C(7) chains propagating along the b-axis direction.
organic compounds
Open access
In the title compound, C20H17N3O4, the dihedral angles between the heterocyclic ring and the toluene and nitrobenzene rings are 4.21 (15) and 11.43 (14)°, respectively. The whole molecule is close to planar (r.m.s. deviation for the 27 non-H atoms = 0.171 Å). Two S(6) rings are formed due to intramolecular C—HO and O—HO hydrogen bonds. In the crystal, inversion dimers linked by pairs of C—HO bonds generate R22(10) loops and further C—HO bonds link the dimers along the b-axis direction. There exist π–π interactions between the heterocyclic rings at a centroid–centroid distance of 3.7126 (10) Å and between the centroids of the benzene rings at a distance of 3.8710 (16) Å.