Crystallization, preliminary X-ray analysis and biophysical characterization of HPr kinase/phosphatase of Mycoplasma pneumoniae

The M. pneumoniae HPr kinase/phosphatase (HPrK/P) was crystallized in the space group P2₁2₁2₁, with unit-cell parameters a = 117.1, b = 127.7, c = 170.7 Å. Both X-ray and biophysical data indicate that HPrK/P is a functional hexamer that undergoes an ATP-binding-induced conformational change.