IYCr crystallization series
Despite possessing an N-terminal F-BAR domain, the srGAP2 protein regulates neurite outgrowth and neuronal migration by causing membrane protrusions reminiscent of the activity of I-BAR domain proteins. In this study, the F-BAR domain of human srGAP2 was crystallized and diffracted to 3.50 Å resolution.
structural communications
Structures of the kinase domain of human tau-tubulin kinase 1 both without and with a bound inhibitor are reported.
crystallization communications
Gos1 protein (Golgi SNAP receptor complex member 1) is involved in the SNAREs complexes which are the core machinery driving membrane fusion between cargo-carrying vesicles and their target membranes in the secretory and endocytic pathways in yeast. In this paper, the crystallization method of truncated versions of the Gos1 protein from Saccharomyces cerevisiae is reported and preliminary data on its X-ray analysis are provided.