Purification, crystallization and preliminary X-ray analysis of the inverse F-BAR domain of the human srGAP2 protein

Despite possessing an N-terminal F-BAR domain, the srGAP2 protein regulates neurite outgrowth and neuronal migration by causing membrane protrusions reminiscent of the activity of I-BAR domain proteins. In this study, the F-BAR domain of human srGAP2 was crystallized and diffracted to 3.50 Å resolution.