3-(4-Hexyl­oxyphen­yl)-1,2,4-triazolo[3,4-b]benzo­thia­zole

The title compound, C₂₀H₂₁N₃OS, was prepared by Huisgen reaction of 5-(4-hexyl­oxyphen­yl)tetra­zole and chloro­benzo­thia­zole. The essentially planar benzo­thia­zolotriazole framework [maximum deviation from the mean plane of 0.077 (1) Å for the bridgehead N atom] and the phenyl ring form a dihedral angle of 53.34 (5)°. The hex­yloxy chain adopts a gauche-all-anti conformation. The intra­centroid separation of 3.7258 (8) Å between the triazole and benzene rings is the closest contact between individual mol­ecules in the crystal.

2-(3-{(3R,4R)-4-Methyl-3-[meth­yl(7H-pyrrolo­[2,3-d]pyrimidin-4-yl)amino]­piperidin-1-yl}oxetan-3-yl)aceto­nitrile monohydrate

In the title compound, C₁₈H₂₄N₆O·H₂O, the piperidine ring adopts a chair conformation with an N-C-C-C torsion angle of 39.5 (5)° between the cis-related substituents. The pyrrole N-H group forms a water-mediated inter­molecular hydrogen bond to one of the N atoms of the annelated pyrimidine ring. The water mol­ecule connects two organic mol­ecules and is disorderd over two positions (occupancies of 0.48 and 0.52). The crystal packing shows zigzag chains of alternating organic and water mol­ecules running parallel to the a axis.

Crystal structure of ethyl 2-(di­eth­oxy­phosphor­yl)-2-(2,3,4-tri­meth­oxy­phen­yl)acetate

The title compound, C₁₇H₂₇O₈P, was prepared by Michaelis–Arbuzov reaction of ethyl 2-bromo-2-(2,3,4-tri­meth­oxy­phen­yl)acetate and triethyl phosphite. Such compounds rarely crystallize, but single crystals were recovered after the initial oil was left for approximately 10 years. The bond angle of the sp³-hybridized C atom connecting the benzene derivative with the phospho unit is widened marginally [112.5 (2)°]. The terminal P—O bond length of 1.464 (2) Å clearly indicates a double bond, whereas the two O atoms of the eth­oxy groups connected to the phospho­rous atom have bond lengths of 1.580 (2) Å and 1.581 (3) Å. The three meth­oxy groups emerge out of the benzene-ring plane due to steric hindrance [C—C—O—C torsion angles = −179.9 (3)°, −52.9 (4)° and 115.3 (4)°]. In the crystal, inversion dimers linked by pairs of C—H...O=P hydrogen bonds generate R₂²(14) loops. The chosen crystal was modelled as a non-merohedral twin.