Crystallographic snapshots of initial steps in the collapse of the calmodulin central helix

Novel bent conformations of the calmodulin central helix are presented. The structures may relate to the initial stages of structural collapse in calmodulin upon target-peptide binding.

Atomic resolution view into the structure-function relationships of the human myelin peripheral membrane protein P2

The structure of the human myelin peripheral membrane protein P2 has been refined at 0.93 Å resolution. In combination with functional experiments in vitro, in vivo and in silico, the fine details of the structure-function relationships in P2 are emerging.