Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain

The crystal structure of ShSPI, a serpin from the blood fluke S. haematobium, reveals some peculiar features of the helical subdomain which have not been observed previously in the serpin superfamily.

Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction

The structure of the VibB ISC domain in complex with isochorismate was determined at atomic resolution. The positions of both of the catalytic waters are significantly affected by the mutation of Asp35 and Lys118.