Journal of Synchrotron Radiation
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J. Synchrotron Rad.
(2014).
21
,
801-810
https://doi.org/10.1107/S1600577514011424
Download PDF of article
Download citation
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Spatial and temporal distribution of γH2AX fluorescence in human cell cultures following synchrotron-generated X-ray microbeams: lack of correlation between persistent γH2AX foci and apoptosis
D. L. Anderson
,
R. Mirzayans
,
B. Andrais
,
E. A. Siegbahn
,
B. G. Fallone
and
B. Warkentin
Immunofluorescence microscopy is used to investigate DNA damage formation, DNA repair and apoptosis in cultured normal human fibroblasts and human malignant glioma cells exposed to synchrotron-generated microbeams.
Keywords:
microbeam
;
γH2AX
;
X-rays
;
radiation therapy
;
DNA damage
;
apoptosis
.
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