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The S. pyogenes ORF SPy1599, classified into CAZy family GH1, has been shown to display 6-phospho-β-glucosidase activity through a series of kinetics studies on aryl glycosides. The three-dimensional structure has been solved at 2.5 Å resolution from both twinned and untwinned crystal forms.

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An introduction to the proceedings of the CCP4 Study Weekend held at the University of Warwick on the 5-6 January 2012.

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Structures of the B. subtilis dUTPases in a novel complex with dU-PPi-Mg2+ and in complex with dUMP provide insights into the mechanism and identify features unique to the B. subtilis enzymes.
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