Structure determination from a single high-pressure-frozen virus crystal

High-pressure-freezing allowed low-temperature data collection from a single virus crystal for which no standard cryoprotection could be established.

Visualization of membrane protein crystals in lipid cubic phase using X-ray imaging

A comparison of X-ray diffraction and radiographic techniques for the location and characterization of protein crystals is demonstrated on membrane protein crystals mounted within lipid cubic phase material.

Microcrystal manipulation with laser tweezers

Optical trapping has successfully been applied to select and mount microcrystals for subsequent X-ray diffraction experiments.