Structure of a double-stranded DNA (6-4) photoproduct in complex with the 64M-5 antibody Fab

The crystal structure of a double-stranded DNA (6-4) photoproduct in complex with the anti-(6-4)-photoproduct antibody Fab was determined at 2.5 Å resolution. The T(6-4)T segment and the 5'-side adjacent adenosine are flipped out of the DNA duplex and the DNA helices are sharply kinked at the T(6-4)T segment.