Structure of the autophagic E2 enzyme Atg10

The structure of the autophagic E2 conjugating enzyme Atg10 has been determined at 2.7 Å resolution. Unique features of Atg10 compared with other E2 enzymes, including Atg3, another autophagic E2 enzyme, are described.

Structures of the ribosome-inactivating protein from barley seeds reveal a unique activation mechanism

Crystal structures of ribosome-inactivating protein (RIP) from barley seeds have been determined in free, AMP-bound and adenine-bound states. These data revealed a unique activation mechanism for a type I RIP from a monocotyledonous crop.