editorial
An overview of current topics of interest in the field of solid-state pharmaceuticals and an introduction to papers featured in this special issue.
Keywords: Editorial.
pharmaceuticals and natural products
Density functional theory (DFT) NMR prediction, 1H–1H Total Correlated Spectroscopy (TOCSY) NMR and single-crystal X-ray crystallography were used to confirm the formation of a bis-cyclopentenyl-β-cyanohydrin in preference to a 2,3,6,7-dehydrodecalin-β-cyanohydrin as the kinetic product upon subjecting tri- and tetraene substrates to Ru-catalyzed alkene metathesis.
pharmaceuticals and natural products
Methanesulfonic acid salt forms of carbamazepine and 10,11-dihydrocarbamazepine have been prepared and characterized by a number of analytical techniques, including single-crystal X-ray diffraction at 100 K. The structural data for these complexes were analysed in relation to data derived from other carbamazepine complexes and a redetermination of the apparently anomalous trifluoroacetic acid solvate structure was undertaken.