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Two decades of synchrotron radiation source, instrumentation and methods evolution have greatly accelerated the pace of protein crystallography, which can, via the linking up of synchrotron radiation `PX stations' worldwide, now yield a `genome level' of numbers of experimentally determined protein structures.
research papers
Major developments in the theory of the Laue diffraction technique and of the necessary software, hardware and experimental strategies have led to successful time-resolved studies on the dynamic properties of a range of biological systems, which shed light on future applications of this technique.
research papers
Daresbury Laue software and ESRF CCD yielded highly complete and redundant data to 2.3 Å from a single crystal of the enzyme hydroxymethylbilane synthase (wild type, active form). Detector dynamic range capability and Laue geometry are analysed.
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