organic compounds
The title compound, C10H8N2O4S, serves as a starting material for the synthesis of antihyperglycemic pharmaceuticals. The nearly planar thiazolidine-2,4-dione ring is almost perpendicular to the nitrophenyl ring.
organic compounds
The title compound, C8H7NO2, serves as an intermediate for the synthesis of citalopram. The packing of the planar molecules is stabilized by N—HO and N—HN hydrogen bonds.
organic compounds
The title compound, C8H5BrO2, serves as a starting material for the synthesis of citalopram. It crystallizes with two almost identical molecules in the asymmetric unit.
organic compounds
The title compound, C9H13NO, is the key intermediate for the synthesis of the antidiabetic drug pioglitazone and it is used as a versatile intermediate in the synthesis of a number of biologically active novel heterocycles. Both side-chains are located on the same side of the aromatic ring. The molecules are connected by O—HN hydrogen bonds into ribbons which show a herring-bone-like pattern.
organic compounds
The title compound, C12H12BrNO4S, belongs to the class of substituted thiazolidine-2,4-diones. Compounds of this type are important starting materials in pharmaceutical chemistry. The thiazolidine-2,4-dione ring is disordered about a twofold rotation axis. Geometric parameters, other than those of the disordered groups, are in the normal ranges.
organic compounds
The title compound, C16H18N2O2, is a key intermediate for the synthesis of biologically active novel heterocycles, e.g. isoxazolines and isoxazoles. Geometric parameters of the molecule are in the usual ranges. The crystal packing is stabilized by an O—HN hydrogen bond.
organic compounds
The title compound, C33H25BrN4, belongs to the class of substituted tetrazoles. This type of compound is an important starting material for the synthesis of pharmaceutically active materials.