organic compounds
The title compound, C16H15NO3S, was prepared by base-catalyzed reaction of 3,4,5-trimethoxybenzaldehyde with thiophene-3-acetonitrile. The olefinic bond has Z geometry and thienyl ring flip disorder is observed.
organic compounds
The title compound, C11H8Cl2N2S, was prepared from the condensation reaction of thiophene-3-carbaldehyde with 2,5-dichlorophenylhydrazine. The azomethine C=N bond has E geometry. No thienyl ring flip was observed.
organic compounds
Crystals of the title compound, which is also commonly known as 6-O-acetylcodeine, C20H23NO4, were obtained by acetylation of codeine and subsequent crystallization of the product from ethyl acetate. The atoms of the benzene ring are nearly coplanar, whereas the five-memberedring is distorted. The ethanamine ring has a typical chair form conformation, while the cyclohexene ring is in a twisted boat form.
organic compounds
The title compound {systematic name: (1R,2R,5R)-(+)-2-hydroxy-2,6,6-trimethyl-3-[(3-pyridyl)methylimino]bicyclo[3.1.1]heptane}, C16H22N2O, was obtained by the condensation reaction of (1R,2R,5R)-(+)-2α-hydroxypinan-3-one with 3-(aminomethyl)pyridine in the presence of boron trifluoride. The compound was obtained as an enantiomerically pure isomer, and has the 1R,2R,5R configuration. In the crystal structure, molecules are linked together by intermolecular O—HN hydrogen bonds between the hydroxy group of the pinanone group and the N atom of the pyridine ring, forming molecular chains.
organic compounds
The dihedral angle between the benzene rings in the title compound, C13H6Cl6O, is 49.06 (8)°. The molecule has crystallographic twofold rotation symmetry.
organic compounds
The dihedral angle between the benzene rings in the title compound, C12H5Cl5, is 81.5 (2)°.
organic compounds
The title compound, C14H14N2O3, was prepared by the base-catalyzed condensation reaction of 3-nitrobenzaldehyde with 1-azabicyclo[2.2.2]octan-3-one. The 3-nitrophenyl ring is twisted by 27.29 (19)° with respect to the plane of the C=C double bond connected to the azabicyclic ring. The molecule adopts the Z configuration.
organic compounds
The title compound, C18H17NOS2, was prepared by the base-catalyzed Aldol condensation of tropinone with thiophene-3-carboxaldehyde. It crystallizes with the molecule on a mirror plane. Both double bonds linking the tropinone and thiophene rings adopt the E configuration, with the thienyl-ring flip and the H atoms of the N-methyl group disordered.