organic compounds
Open access
In the title molecule, C13H14N2O3S, the dihydropyrimidine ring is in a flattened sofa conformation, with the methine C atom forming the flap. The dihedral angle between the mean plane of the five essentially planar atoms of the dihydropyrimidine ring [maximum deviation = 0.056 (4) Å] and the benzene ring is 89.4 (2)°. The O atom of the carbonyl group is in a trans conformation with respect to the C=C bond of the dihydropyrimidine ring. In the crystal, N—HO and O—HS hydrogen bonds connect molecules, forming a two-dimensional network parallel to (001).
organic compounds
Open access
In the title compound, C14H9F3N2, the mean planes of the benzimidazole ring system and the trifluoromethyl-substituted benzene ring form a dihedral angle of 30.1 (1)°. In the crystal, molecules are linked by N—HN hydrogen bonds into chains along [010]. Weak C—HF hydrogen bonds and a weak C—Hπ interaction connect the chains into a two-dimensional network parallel to (001).
data reports
Open access
In the title molecule, C23H18F2N2O3S, the pyrimidine ring is in a half-chair conformation and the 3-fluorophenyl group is in the axial position. The thiazole ring (r.m.s. deviation = 0.0252 Å) forms dihedral angles of 84.8 (7) and 9.6 (7)° with the 3-fluoro-substituted and 4-fluoro-substituted benzene rings, respectively. In the crystal, weak C—HF and C—HO hydrogen bonds connect molecules, forming zigzag chains along the b axis. In addition π–π stacking interactions with a centroid–centroid distance of 3.7633 (9) Å connect these chains into ladders via inversion-related 4-fluorophenyl groups.