organic compounds
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The asymmetric unit of the title salt [systematic name: 1-benzhydryl-4-cinnamylpiperazine-1,4-diium bis(p-toluenesulfonate) dihydrate], C26H30N22+·2C7H7O3S−·2H2O, consists of a diprotonated cinnarizinium cation hydrogen bonded through two water molecules to two independent p-toluenesulfonate anions, one which is disordered over two sets of sites in a 0.793 (3):0.207 (3) ratio. In the cation, the piperazine ring adopts a chair configuration and contains two positively charged N atoms with quarternery character. The dihedral angle between the two benzene rings in the benzhydryl group is 71.8 (1)°. The benzene ring flanked opposite the piperazine ring is twisted by 75.9 (9) and 8.8 (3)° from these two benzene rings. In the crystal, the [N—HOwater—HO(S)]2 hydrogen-bonded asymmetric unit is connected by further O—HO hydrogen bonds linking the components into chains along [100].
organic compounds
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In the title compound, C11H8Cl2N2OS, the mean plane of the dichlorophenyl ring is twisted by 79.7 (7)° from that of the thiazole ring. In the crystal, molecules are linked via pairs of N—HN hydrogen bonds, forming inversion dimers which stack along the a-axis direction.
organic compounds
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The molecule of the title compound, C12H14N4O, is roughly planar, with a dihedral angle of 8.0 (8)° between the benzene and pyrazole rings, and an intramolecular N—HO hydrogen bond forms an S(6) ring motif. In the crystal, molecules are linked into an inversion dimer by a pair of N—HO hydrogen bonds, which form an R22(8) ring motif.
organic compounds
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Three independent molecules comprise the asymmetric unit of the title compound, C10H19N5O2, (systematic name: 4-amino-N-tert-butyl-3-isopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-carboxamide) . In all three molecules, the triazole ring and the carboxamide group are almost coplanar [within 4.0–5.9 (9)°], particularly because of the formation of an intramolecular N—HO hydrogen bond. On other hand, the orientation of the isopropyl group varies significantly from molecule to molecule. The crystal packing is dominated by N—HO and N—HN hydrogen bonds, which connect the molecules into infinite chains along [010].