Eight salt forms of sulfadiazine

A. R. Buist, L. Dennany, A. R. Kennedy, C. Manzie, K. McPhie and B. Walker

Eight crystal structures of protonated forms of the sulfa drug sulfadiazine are presented. Sulfonate-containing anions support a different tautomeric form of the sulfadiazine cation than that supported by other anions.

Keywords: crystal structure; sulfa drugs; sulfadiazine; salt forms; tautomerism; pharmaceutical compounds; tetraiodide; active pharmaceutical ingredients (APIs).

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