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The title compound, C17H19N3O2, crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. In both mol­ecules, the pyran ring has a twisted conformation (5S4), with Q = 0.301 (3) Å, θ = 116.7 (6) and φ= 213.6 (7)° for mol­ecule A, and Q = 0.364 (2) Å, θ = 113.7 (3) and φ = 213.0 (4)° for mol­ecule B. In mol­ecule B, the terminal ethyl group is disordered over two orientations with an occupancy ratio of 0.55 (1):0.45 (1). In the crystal, mol­ecules A and B form very similar but separate R12(7) motifs through N—H...O and C—H...O hydrogen bonds. The resulting chains along [001] are inter­linked by weaker C—H...O and C—H...π inter­actions, forming layers parallel to the bc plane.

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The mol­ecular structure of the title compound, C12H19NO5, may be visualized as made up of two nearly perpendicular planes [dihedral angle = 87.39 (12)°] and its crystal structure is a good example of C—H...O inter­actions assuming significance in optimizing supra­molecular aggregation in crystals in a mol­ecule which is severely imbalanced in terms of donors to acceptor atoms. The pyrrolidine ring adopts a (3T2) twist conformation with puckering parameters Q = 0.2630 (4) Å and φ = 59 (9)°. The crystal structure features R24(10) and R34(26) ring motifs formed by four weak C—H...O inter­actions, leading to supra­molecular sheets lying parallel to the bc plane.

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In the title compound, C17H22FNO4, the pyrrolidine ring adopts an envelope conformation with the disordered com­ponents of the methylene C atom, with site occupancies of 0.896 (7) and 0.104 (7), being the flap on either side of the mean plane involving the other atoms of the ring. The carb­oxy­lic acid group forms dihedral angles of 72.06 (11) and 45.44 (5)° with the N-tert-but­oxy­carbonyl group and the 2-fluoro­benzyl group, respectively. In the crystal, two-dimensional layers of mol­ecules parallel to (001) are built through an R44(23) motif generated via O—H...O, C—H...O and C—H...F inter­actions, and an R22(11) motif generated by C—H...O and C—H...F inter­actions.
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