Acta Crystallographica Section D
Acta Crystallographica
Section D
STRUCTURAL BIOLOGY
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Acta Cryst.
(2014).
D
70
,
68-78
https://doi.org/10.1107/S1399004713025030
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Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the molecules
J. Nomme
,
J. M. Murphy
,
Y. Su
,
N. D. Sansone
,
A. L. Armijo
,
S. T. Olson
,
C. Radu
and
A. Lavie
This article describes the structural and biochemical characterization of a new class of high-affinity and selective human deoxycytidine kinase inhibitors.
Keywords:
deoxycytidine kinase
;
inhibitors
;
nucleotide salvage pathway
.
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