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The mol­ecular structure of the title compound, C11H13IN4O3, shows a ribo­furanos­yl–pyrrolo O—C—N—C torsion angle of 59.1 (3)°, with the central C—N bond length being 1.446 (3) Å. The C—I bond length is 2.072 (2) Å. The amino group is coplanar with the attached aromatic ring [C—N—C—N torsion angle = −178.8 (2)°] and forms an intra­molecular N—H...I hydrogen bond. In the crystal, O—H...N and N—H...O hydrogen bonds link the mol­ecules into puckered layers parallel to (001). These layers are bound to each other by secondary I...O inter­actions [3.2250 (17) Å], forming a three-dimensional framework.
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