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In the title compound, C16H15N3O4, the dihedral angle between the chromane and isoxazole rings [r.m.s. deviations = 0.042 and 0.007 Å, respectively] is 20.33 (12)°. The mol­ecular geometry is stabilized by an intra­molecular N—H...O hydrogen bond. In the crystal, N—H...O hydrogen bonds generate chains along the c-axis direction. The crystal studied was a non-morohedral twin.
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