organic compounds
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In the title compound, C16H9Cl2N5O2, the folded molecular conformation is characterized by a dihedral angle between the two benzene rings of 74.03 (5)°. An intramolecular N—HO hydrogen bond is observed between the H atom of the amide group and a nitro-group O atom. Intermolecular C—HO and N—HN hydrogen bonds feature in the crystal packing.
organic compounds
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In the title compound, C20H11Cl2F4N3, the central pyrazolo[1,5-a]pyrimidine unit is almost planar [the mean deviation from the best least-square plane through the nine atoms is 0.006 (2) Å]. The fluorobenzene ring is rotated out of this plane by 10.3 (3)°, whereas the dichlorobenzene ring is rotated by 46.2 (3)°. The crystal packing is dominated by ClCl interactions of 3.475 (3) Å and van der Waals interactions.
organic compounds
Open access
In the title compound, C25H13Cl2F4N3, there are four planar systems, viz. three benzene rings and a pyrazolo[1,5-a]pyrimidine system [r.m.s. deviation = 0.002 Å]. The dihedral angle between the dichlorophenyl ring and the unsubstituted phenyl ring is 69.95 (5)°, while that between the fluorophenyl ring and the unsubstituted phenyl ring is 7.97 (10)°. The crystal packing is dominated by van der Waals interactions. A ClCl interaction of 3.475 (3) Å also occurs.
organic compounds
Open access
In the title compound, C34H41N7O5·4H2O (systematic name: ethyl 3-{[2-({4-[(Z)-amino(hexyloxycarbonylimino)methyl]anilino}methyl)-1-methylbenzimidazole-5-carbonyl]pyridin-2-ylamino}propanoate tetrahydrate), the benzene and pyridine rings form dihedral angles of 5.4 (1) and 43.8 (1)°, respectively, with the benzimidazole mean plane. The terminal butyl group is disordered over two conformations in a 0.756 (10):0.244 (10) ratio. There is an intramolecular N—HO hydrogen bond present. In the crystal, the water molecules are involved in the formation of O—HO, O—HN and N—HO hydrogen bonds, which link the components into layers parallel to the ab plane.