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organic compounds
Polymorph VI of 4-amino-N-(2-pyridyl)benzenesulfonamide, C11H11N3O2S, is monoclinic (space group P21/n). The asymmetric unit contains two different tautomeric forms. The structure displays N—H
N and N—HO hydrogen bonding. The two independent molecules form two separate two- and three-dimensional hydrogen-bonded networks which interpenetrate. The observed patterns of hydrogen bonding are analogous to those in polymorph I of sulfathiazole.
N and N—HO hydrogen bonding. The two independent molecules form two separate two- and three-dimensional hydrogen-bonded networks which interpenetrate. The observed patterns of hydrogen bonding are analogous to those in polymorph I of sulfathiazole.organic compounds
The structure of the title compound (systematic name: 2-{2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetoxy}acetic acid monohydrate, C21H18ClNO6·H2O) contains one-dimensional infinite hydrogen-bonded chains. Molecules of acemetacin, a nonsteroidal anti-inflammatory drug, and water are linked by three independent O—HO bonds. The central unit in each chain consists of a sequence of alternating centrosymmetric R44(12) and R44(18) rings, which are edge-fused. Each ring links two acemetacin and two water molecules. A comparison with seven related structures reveals that molecules of acemetacin, indomethacin and their analogues can adopt two principal conformations.
O bonds. The central unit in each chain consists of a sequence of alternating centrosymmetric R44(12) and R44(18) rings, which are edge-fused. Each ring links two acemetacin and two water molecules. A comparison with seven related structures reveals that molecules of acemetacin, indomethacin and their analogues can adopt two principal conformations.organic compounds
N-HO bonding in a form of 5-butyl-5-ethylbarbituric acid (systematic name: 5-butyl-5-ethyl-1,3-diazinane-2,4,6-trione), C10H16N2O3, produces two distinct one-dimensional motifs, viz. tape and ladder. Both are different from the ribbon chain motif observed in two previously reported polymorphs of the same compound.
O bonding in a form of 5-butyl-5-ethylbarbituric acid (systematic name: 5-butyl-5-ethyl-1,3-diazinane-2,4,6-trione), C10H16N2O3, produces two distinct one-dimensional motifs, viz. tape and ladder. Both are different from the ribbon chain motif observed in two previously reported polymorphs of the same compound.
