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In the title compound, C21H20BrNO5S, the thio­phene group is located above the mean plane of the indole ring and displays rotational disorder (i.e. rotation through 180°). The site occupancy of the major component is 0.902 (2), while that of the minor component is 0.098 (2). In the crystal, pairs of weak C—H...O inter­actions link the mol­ecules into centrosymmetric dimers.
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