Structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa: the binary complex with the cofactor NAD⁺

The crystal structure of NAD⁺-bound FDH from P. aeruginosa was determined to 2.7 Å resolution. The overall structure is very similar to that of P. putida FDH. Preliminary kinetics analysis of the enzyme indicated a glutathione-independent bi-substrate `ping-pong' catalytic mechanism.

Structure of zebrafish MO25

The conserved protein MO25 activates STE20 family kinases. The crystal structure of zebrafish MO25 is reported, which is similar to that of human MO25.