Acta Crystallographica Section F
Acta Crystallographica
Section F
STRUCTURAL BIOLOGY COMMUNICATIONS
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Acta Cryst.
(2012).
F
68
,
404-408
https://doi.org/10.1107/S1744309112009037
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High-resolution crystal structures of factor XIa coagulation factor in complex with nonbasic high-affinity synthetic inhibitors
X. Fradera
,
B. Kazemier
,
E. Carswell
,
A. Cooke
,
A. Oubrie
,
W. Hamilton
,
M. Dempster
,
S. Krapp
,
S. Nagel
and
A. Jestel
Two structures of factor XIa in complex with small synthetic inhibitors are reported. These are the first structures of factor XIa complexed to small non-basic inhibitors.
Keywords:
factor XIa
;
inhibitors
;
coagulation factors
.
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