Increase of lifespan for glioma-bearing rats by using minibeam radiation therapy

A new radiotherapy technique, minibeam radiation therapy, combining submillimetric field sizes and a spatial fractionation of the dose is under development at the biomedical beamline of the ESRF. Here the therapeutic effectiveness of single-fraction minibeam radiation therapy on 9L gliosarcoma-bearing rats is assessed.

Chalcone JAI-51 improves efficacy of synchrotron microbeam radiation therapy of brain tumors

The association of microbeam radiation therapy with chemotherapeutic agent JAI-51 has been evaluated for the treatment of 9LGS implanted in rat brains, particularly the effects on the median survival time of the rats. The effects of both treatments, alone or combined, on the tumor cell cycle ex vivo have been characterized.