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The title compound, C16H16N2O5, is a β-ketoether derivative closely related to natural 8,4′-oxyneolignans, which are of interest because of their moderate antifungal activity against systemic mycosis. The nitro group is not coplanar with the aromatic ring, as shown by a torsion angle of 47.2 (4)°. The molecules are linked by two non-classical intermolecular C—H...O hydrogen bonds with distances between donors and acceptors of 3.441 (5) and 3.539 (5) Å, leading to the formation of molecular stacking perpendicular to the bc plane.
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