Crystal structure of [4-(2-meth­oxy­phen­yl)-3-methyl-1-phenyl-6-tri­fluoro­methyl-1H-pyrazolo­[3,4-b]pyridin-5-yl](thio­phen-2-yl)methanone

The title compound, C₂₆H₁₈F₃N₃O₂S, a 2-meth­oxy-substituted derivative, is closely related to its 4-methyl- and 4-chloro-substituted analogues and yet displays no structural relationships with them. The thio­phene ring is disorder free and the –CF₃ group exhibits disorder, respectively, in contrast and similar to that observed in the 4-methyl- and 4-chloro-substituted derivatives. The torsion angle which defines the twist of the thio­phene ring is −69.6 (2)° (gauche) in the title compound, whereas it is anti­clinal in the 4-methyl- and 4-chloro-substituted derivatives, with respective values of 99.9 (2) and 99.3 (2)°. The absence of disorder in the thio­phene ring facilitates one of its ring C atoms to participate in the lone inter­molecular C—H...O hydrogen bond present in the crystal, leading to a characteristic C(5) chain graph-set motif linking mol­ecules related through glides along [010]. An intra­moleculr C—H...N hydrogen bond also occurs.

Crystal structure of 4-sulfamoylanilinium di­hydrogen phosphate

In the crystal structure of the title mol­ecular salt, C₆H₉N₂O₂S⁺·H₂PO₄⁻, the sulfomylalinium cations and the di­hydrogen phosphate anions form independent [100] chains through N_s—H...O (s = sulfamo­yl) and O—H...O hydrogen bonds, respectively. The chains are cross-linked by N_a—H...O (a = amine) hydrogen bonds, generating (010) sheets. Two C—H...O hydrogen bonds involving diametrically opposite C atoms in the benzene ring of the cation as donors form chains parallel to [202] in which P=O and P—OH groups are acceptors. Together, these inter­actions lead to a three-dimensional network.