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The title compound, C30H28ClN3O2, features two spiro links, one connecting the piperidine and pyrrolidine rings, and the other connecting the pyrrolidine ring and indole residue. The configuration about the ethene bond is E. The piperidine ring adopts a half-chair conformation where the C atom connected to the spiro-C atom lies 0.713 (3) Å out of the plane of the remaining five atoms (r.m.s. deviation = 0.086 Å). The pyrrolidine ring has an envelope conformation with the flap atom being the methyl­ene C atom. Centrosymmetric eight-membered {...HNCO}2 amide synthons feature in the crystal packing. These are consolidated into a three-dimensional architecture by phen­yl–pyrrolidine C—H...N and chloro­benzene–pyrrolidine-bound phenyl C—H...π inter­actions.

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Two spiro links are found in the title compound, C31H28Cl3N3O2, one connecting the piperidine and pyrrolidine rings, and the other connecting the pyrrolidine ring and indole residue. The piperidine ring adopts a half-chair conformation, in which the C atom connected to the spiro-C atom lies 0.741 (3) Å out of the plane of the remaining five atoms (r.m.s. deviation = 0.053 Å). The pyrrolidine ring has an envelope conformation with the flap atom being the methyl­ene C atom. Centrosymmetric eight-membered {...HNCO}2 amide dimers are the most significant feature of the crystal packing. These are connected into layers parallel to (-120) by C—H...O and π–π inter­actions between pyrrolidine-bound benzene rings [inter-centroid distance = 3.8348 (15) Å]. Slipped face-to-face inter­actions between the edges of pyrrolidine-bound benzene [shortest C...C separation = 3.484 (4) Å] connect the layers into a three-dimensional architecture.

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The title compound, C34H38ClN5O2, has spiro links connecting the pyrrolidine ring and indole residue, as well as the piperidine and pyrrolidine rings. A half-chair conformation is found for the piperidine ring with the C atom connected to the spiro-C atom lying 0.738 (4) Å out of the plane of the remaining five atoms (r.m.s. deviation = 0.0407 Å). The methyl­ene C atom is the flap in the envelope conformation for the pyrrolidine ring. In the crystal, supra­molecular chains are sustained by alternating eight-membered {...HNCO}2 and 14-membered {...HC5O}2 synthons. Chains are connected into a three-dimensional network by (pyrrolidine-bound phenyl-meth­yl)C—H...π(pyrrolidine-bound phen­yl) edge-to-face inter­actions.

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The title complex, [Cu{μ3-O2CC6H3(NO2)2-3,5}(μ-OH)]n, features zigzag chains in which successive pairs of CuII atoms are connected by OH bridges and bidentate carboxyl­ate ligands, leading to six-membered Cu(O)(OCO)Cu rings. The zigzag chains are connected into a three-dimensional architecture by Cu—O(nitro) bonds. The coordination geometry of the CuII atom is square-pyramidal, with the axial position occupied by the nitro O atom, which forms the longer Cu—O bond. Bifurcated hy­droxy–nitro O—H...O hydrogen bonds contribute to the stability of the crystal structure.

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The 21 non-H atoms of the title compound, C15H10Cl2N4, are almost planar (r.m.s. deviation = 0.032 Å); the conformation about the N=C bond [1.277 (6) Å] is E. In the crystal, zigzag supra­molecular chains along the c axis (glide symmetry) are formed via N—H...N hydrogen bonds. These associate along the b axis by π–π inter­actions between the fused and terminal benzene rings [inter­centroid distance = 3.602 (3) Å] so that layers form in the bc plane.

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In the title compound, C14H8N4O6, the benzoxazin-4-one fused-ring system (r.m.s. deviation = 0.018 Å) is coplanar with the attached benzene ring [dihedral angle = 0.81 (4)°], there being an intra­molecular N—H...N hydrogen bond between them. Each nitro group is twisted out of the plane of the attached benzene ring [O—N—C—C torsion angles = 167.94 (11) and 170.38 (11)°]. In the crystal, amine–nitro N—H...O hydrogen bonds lead to centrosymmetric dimeric aggregates that are connected into a three-dimensional architecture by oxazin­yl–nitro C—H...O and π–π inter­actions [inter-centroid distance between the oxazinyl and terminal benzene rings = 3.5069 (7) Å].

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In the title compound, C8H7N3O4 (systematic name: 4-nitro­benzene-1,2-dicarboxamide), each of the substituents is twisted out of the plane of the benzene ring to which it is attached [dihedral angles of 11.36 (2)° for the nitro group, and 60.89 (6) and 34.39 (6)° for the amide groups]. The amide groups are orientated to either side of the least-squares plane through the benzene ring with the amine groups being directed furthest apart. In the crystal, a three-dimensional architecture is established by a network of N—H...O hydrogen bonds.

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In the title compound, C8H3N3O2 (systematic name: 4-nitro­benzene-1,2-dicarbo­nitrile), the nitro group is twisted out of the plane of the benzene ring to which it is attached [O—N—Cring—Cring torsion angle = 9.80 (13)°]. In the crystal packing, supra­molecular layers with a zigzag topology in the ac plane are sustained by C—H...N inter­actions.

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The asymmetric unit of the title cyclic thio­urea derivative, C10H12N2S, comprises two mol­ecules, each of which has a twist about the CH2—CH2 bond within the five-membered ring. The major difference between the independent mol­ecules is manifested in the relative orientations of the five- and six-membered rings [dihedral angles between the least-squares planes = 28.03 (11) and 41.54 (11)°]. A network of C—H...π inter­actions consolidates the three-dimensional crystal packing.

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In the title salt, C11H12ClN2O+·Cl, the ten non-H atoms comprising the quinolinium residue are coplanar (r.m.s. deviation = 0.041 Å) and the hy­droxy­ethyl group is approximately perpendicular to this plane [Cring—N—Cmethyl­ene—C torsion angle = −74.61 (18)°]. A supra­molecular chain aligned along [101] mediated by charge-assisted O/N—H...Cl hydrogen bonds features in the crystal packing. Chains are connected into a three-dimensional architecture by C—H...O(hy­droxy) inter­actions.

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The sulfa­thia­zole mol­ecule in the title 1:1 co-crystal, C9H9N3O2S2·C18H12N6, adopts an approximate L-shape [dihedral angle between the five- and six-membered rings = 86.20 (9)°] and features an intra­molecular hypervalent S...O inter­action [2.8666 (15) Å]. Overall, the triazine mol­ecule has the shape of a disk as the pendant pyridine rings are relatively close to coplanar with the central ring [dihedral angles = 18.35 (9), 6.12 (9) and 4.67 (9)°]. In the crystal packing, a linear supra­molecular chain aligned along [01-1] is formed as a result of amino–pyridyl N—H...N hydrogen bonding with syn-disposed pyridyl mol­ecules of one triazine, and amine–pyridyl N—H...N hydrogen bonding with the third pydridyl ring of a second triazine mol­ecule. A three-dimensional architecture arises as the chains are connected by C—H...O inter­actions.

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The title compound, C15H24O2 [systematic name: (4S,4aR,6R,8aR)-4a-hy­droxy-4,8a-dimethyl-6-(prop-1-en-2-yl)octahydro­naphthalen-1(2H)-one], features two edge-shared six-membered rings with the hydroxyl and methyl substituents at this bridge being trans. One adopts a flattened chair conformation with the C atoms bearing the carbonyl and methyl substituents lying 0.5227 (16) and 0.6621 (15) Å, respectively, above and below the mean plane through the remaining four C atoms (r.m.s. deviation = 0.0145 Å). The second ring, bearing the prop-1-en-2-yl group, has a chair conformation. Supra­molecular helical chains along the b axis are found in the crystal packing, which are sustained by hy­droxy–carbonyl O—H...O hydrogen bonding.

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Four independent mol­ecules (AD) comprise the asymmetric unit of the title compound, C15H26O2, which differ only in the relative orientations of the terminal –C(Me)2OH groups [e.g. the range of Cmethyl­ene—Cmethine—Cquaternary—Ohy­droxy torsion angles is 52.7 (7)–57.1 (6)°, where the Cmethyl­ene atom is bound to an epoxide C atom]. The five-membered rings adopt envelope conformations, with the methyl­ene C atom adjacent to the methine C atom being the flap atom in each case. In each mol­ecule, the conformation of the seven-membered ring is a half-chair, with the Cmethyl­ene—Cmethine bond, flanked by methyl­ene C atoms, being the back of the chair. Supra­molecular helical chains along the b axis are found in the crystal packing, sustained by hy­droxy–epoxide O—H...O hydrogen bonding. Mol­ecules of A self-associate into a chain as do those of D. A third independent chain comprising B and C mol­ecules is also formed. The studied crystal is a pseudo-merohedral twin (minor component ca 21%).

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In the title compound, C17H15NO4, the conformation about the C=C double bond [1.348 (2) Å] is E with the ketone group almost co-planar [C—C—C—C torsion angle = 7.2 (2)°] but the phenyl group twisted away [C—C—C—C = 160.93 (17)°]. The terminal aromatic rings are almost perpendicular to each other [dihedral angle = 81.61 (9)°] giving the mol­ecule an overall U-shape. The crystal packing feature benzene-C—H...O(ketone) contacts that lead to supra­molecular helical chains along the b axis. These are connected by π–π inter­actions between benzene and phenyl rings [inter-centroid distance = 3.6648 (14) Å], resulting in the formation of a supra­molecular layer in the bc plane.

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In the title compound, C17H14N2O6, the conformation about the C=C double bond [1.345 (2) Å] is E, with the ketone moiety almost coplanar [C—C—C—C torsion angle = 9.5 (2)°] along with the phenyl ring [C—C—C—C = 5.9 (2)°]. The aromatic rings are almost perpendicular to each other [dihedral angle = 86.66 (7)°]. The 4-nitro moiety is approximately coplanar with the benzene ring to which it is attached [O—N—C—C = 4.2 (2)°], whereas the one in the ortho position is twisted [O—N—C—C = 138.28 (13)°]. The mol­ecules associate via C—H...O inter­actions, involving both O atoms from the 2-nitro group, to form a helical supra­molecular chain along [010]. Nitro–nitro N...O inter­actions [2.8461 (19) Å] connect the chains into layers that stack along [001].

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In the title compound, C15H20BrNO2, there are two independent mol­ecules (A and B) comprising the asymmetric unit and these adopt very similar conformations. In A, the dihedral angle between the CO2 and MeC=CMe2 groups is 80.7 (3)°, and these make dihedral angles of 3.5 (3) and 84.09 (16)°, respectively, with the bromo­benzene ring. The equivalent dihedral angles for mol­ecule B are 78.4 (3), 2.1 (3) and 78.37 (12)°, respectively. The most prominent inter­actions in the crystal packing are amine-N—H...O(carbon­yl) hydrogen bonds between the two independent mol­ecules, resulting in non-centrosymmetric ten-membered {...OC2NH}2 synthons. Statistical disorder is noted for each of the terminal methyl groups of the ethyl residues.

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In the title salt of an S-substituted di­thio­carbazate, C16H16N3S2+·Cl, the dihedral angles between the almost planar (r.m.s deviation = 0.005 Å) central CN2S2 residue and the terminal pyridinium and phenyl rings are 80.09 (11) and 3.82 (11)°, respectively, indicating the cation has an L-shape; the amine H and thione S atoms are syn. The conformation about each of the imine [1.376 (3) Å] and ethene [1.333 (4) Å] bonds is E. The shortened C—C bond [1.444 (4) Å] linking the double bonds is consistent with conjugation in this part of the mol­ecule. In the crystal, supra­molecular layers with a jagged topology are formed by charged-assisted amine-H...Cl and pyridinium-N+—H...Cl hydrogen bonds. The layers stack along the a axis with no specific directional inter­actions between them.
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