3-(3,4-Dimeth­oxy­benz­yl)chroman-4-one

In the title compound, C₁₈H₁₈O₄, the six-membered chroman-4-one ring adopts an envelope conformation with the C atom bonded to the bridging CH₂ atom as the flap. The dihedral angle between the mean plane of the fused pyranone ring and the dimeth­oxy-substituted benzene ring is 89.72 (2)°. In the crystal, adjacent molecules are linked via C—H...π inter­actions.

4-(2H-1,3-Benzodioxol-5-yl)-1-(4-methyl­phenyl)-1H-pyrazol-5-amine

In the title compound, C₁₇H₁₅N₃O₂, two independent mol­ecules (A and B) comprise the asymmetric unit. The major conformational difference arises in the relative orientation of the pyrazole ring amine and dioxole substituents which are anti in A and syn in B. The five-membered dioxole ring in each mol­ecule has an envelope conformation with the methyl­ene C atom as the flap. The mean plane through the benzodioxole and benzene groups make dihedral angles of 31.67 (8) and 68.22 (9)°, respectively, with the pyrazole ring in A; the equivalent values for B are 47.18 (7) and 49.08 (9)°. In the crystal, supra­molecular zigzag chains along the b-axis direction arise as a result of N—H...N hydrogen bonding. These are consolidated into supra­molecular double chains via C—H...O and C—H...π inter­actions.

tert-Butyl 4-{[2-amino-4-(2-hy­droxy­phen­yl)pyrimidin-5-yl]meth­yl}piperazine-1-carboxyl­ate

In the title compound, C₂₀H₂₇N₅O₃, the central piperazine ring adopts a chair conformation, with the N-bound carboxyl­ate and methyl­ene substituents occupying bis­ectional and equatorial orientations, respectively. A twist is evident between the aromatic rings [dihedral angle = 25.61 (9)°] but an intra­molecular O—H...N hydrogen bond persists between these. Supra­molecular tapes along [1-10] are formed in the crystal packing through N(amino)—H...O(hydrox­yl) and N(amino)—H...N(pyrimidin­yl) hydrogen bonds, and these are linked into layers in the ab plane by π–π inter­actions [inter-centroid distance between pyrimidinyl rings = 3.5919 (9) Å].