organic compounds
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In the title compound, C21H23N3O2, the indolin-2-one group is essentially planar, with a maximum deviation of 0.016 (2) Å for the N atom, and makes a dihedral angle of 84.38 (14)° with the benzene ring. The =N—N(H)—C(=O)—C– torsion angle is 0.9 (3)°. In the crystal, molecules are linked into a three-dimensional network via N—HO and C—HO hydrogen bonds. In addition, a C—Hπ interaction was observed.
organic compounds
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In the title compound, C21H20N2O4, the naphthalene ring system makes a dihedral angle of 84.5 (3)° with the benzene ring, and the –C(=O)–N(H)–N(H)–C(=O)– torsion angle is 70.7 (7)°, so that the molecule is twisted. An S(6) ring motif is formed via an intramolecular O—HO hydrogen bond. In the crystal, molecules are linked by N—HO and C–HO hydrogen bonds into supramolecular layers in the ab plane.
organic compounds
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In the title compound, C18H17ClN2O2·C3H6O, the 4H-pyran ring is nearly planar [maximum deviation = −0.108 (1) Å] and the cyclohexene ring is puckered [puckering parameters QT = 0.4596 (17) Å, θ = 55.9 (2)° and φ = 226.5 (3)°]. The 4H-pyran ring is approximately perpendicular to the benzene ring [dihedral angle = 84.35 (7)°] and is almost coplanar with the mean plane of the cyclohexene ring [dihedral angle = 8.64 (7)°]. In the crystal, inversion-related main molecules are linked into dimers by pairs of N—HN hydrogen bonds, generating an R22(12) graph-set motif. These dimers are further connected by N—HO and C—HN hydrogen bonds, forming a layer structure extending parallel to the (011) plane. In addition, the molecules within the layers interact with each other via C—Hπ interactions.
organic compounds
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In the title compound, C21H24N4O2, inversion-related molecules are linked into dimers through pairs of N—HO hydrogen bonds, which generate R22(8) motifs. As well as dimer formation, an additional N—HO hydrogen bond and two C—Hπ contacts, involving H atoms from the phenyl ring and the pyrrole and benzene rings of the indole system, generate a three-dimensional network.
organic compounds
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The 4H-pyran ring of the title compound, C17H16N2O2, is nearly planar [maximum deviation = 0.077 (2) Å] and the cyclohexene ring adopts a flattened chair conformation [puckering parameters: QT = 0.435 (2) Å, θ = 122.0 (3)° and φ = 53.5 (3)°]. The 4H-pyran ring is almost perpendicular to the benzene ring [dihedral angle = 87.23 (8)°] and is almost coplanar with the mean plane of the cyclohexene ring [dihedral angle = 8.01 (8)°]. In the crystal, inversion-related molecules are linked by pairs of intermolecular N—HN hydrogen bonds, forming inversion dimers with R22(12) ring motifs. These dimers are further connected by N—HO and C—HN hydrogen bonds, forming a layer structure extending parallel to (0-12). Molecules within the layers interact with each other via C—Hπ interactions.
organic compounds
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The title compound, C20H23BrN2O2, containing an ibuprofen core, crystallizes with three independent molecules of similar conformation in the asymmetric unit. In these three molecules, the two benzene rings make dihedral angles of 82.7 (2), 71.2 (2) and 78.0 (3)° with respect to each other. The atoms of the isobutyl groups in two of the molecules are disordered over two positions, with site-occupancy ratios of 0.516 (8):0.484 (8) and 0.580 (8):0.420 (8). In the crystal, molecules are linked by N—HO, C—HO and O—HN hydrogen bonds. Furthermore, C—Hπ interactions are also observed.
organic compounds
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In the title 1:1 cocrystal, C10H7NO4·C14H13N3O2, molecules are linked by intermolecular C—HO, N—HO and O—HN hydrogen bonds, forming a three-dimensional network. In addition, π–π stacking interactions [with centroid–centroid distances of 3.5723 (19) and 3.6158 (18) Å] are observed.
organic compounds
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In the crystal structure of the title compound, 2C10H7NO4·C14H13N3O2, the two independent acid molecules are connected through strong O—HN and O—HO hydrogen bonds to the central molecule of the antitubercular drug N′-[(E)-4-methoxybenzylidene]pyridine-4-carbohydrazide. Two such trimolecular units related by an inversion centre interact through a pair of N—HO hydrogen bonds, forming a 3 + 3 molecular aggregate. The dihedral angle between the aromatic rings of the hydrazone molecule is 1.99 (12)°. The crystal packing features weak C—HO and π–π stacking interactions, with centroid–centroid distances of 3.8460 (19) and 3.8703 (13) Å.