3,14-Dimethyl-2,6,13,17-tetra­aza­tricyclo­[16.4.0.0^7,12]docosa­ne–(naphthalen-1-yl)methanol (1/2)

In the title co-crystal, C₂₀H₄₀N₄·2C₁₁H₁₀O, the macrocycle is generated by a crystallographic inversion centre. The N atoms show a pyramidal coordination, and the cyclo­hexane ring that is fused to the 14-membered C₁₀N₄ ring exists in a chair conformation, whereas the methyl substituent occupies an axial site. The (naphthalen-1-yl)methanol mol­ecule forms an O—H...N hydrogen bond to a cyclam N atom. The mean-square-plane passing through the 14-membered ring is approximately coplanar with the naphthalene fused-ring [dihedral angle = 6.6 (1)°].

1-Benzyl-3-methyl-3',5'-diphenyl­spiro­[quinoxaline-2(1H),2'(3'H)-1,3,4-thia­diazole]

In the title spiro compound, C₂₉H₂₄N₄S, the quinoxaline and thia­diazole ring systems share a common C atom; their mean planes are aligned at 87.0 (1)° in one mol­ecule and at 84.1 (1)° in the other independent mol­ecule. The thia­zole ring possesses two aromatic ring substituents and is roughly coplanar with these rings [the dihedral angles between the thia­diazole and phenyl rings are 10.7 (1) and 11.7 (1)° in one mol­ecule, and 16.8 (1) and 17.7 (1)° in the other]. The aromatic ring of the benzyl unit of one mol­ecule is disordered over two orientations in a 1:1 ratio.

2-[((E)-2-{2-[(E)-2-Hy­droxy­benzyl­idene]hydrazinecarbon­yl}hydrazinyl­idene)meth­yl]phenol

The mol­ecule of the title compound, C₁₅H₁₄N₄O₃, is completed by the application of crystallographic twofold symmetry, with the carbonyl group lying on the rotation axis. The mol­ecule is close to planar: the greatest deviation of a torsion angle from 0° is 7.3 (2)° about the bond linking the phenol ring to the rest of the mol­ecule. An intra­molecular O—H...N(imine) hydrogen bond is formed in each half of the mol­ecule. The carbonyl O atom is anti with respect to the amine H atoms and this allows for the formation of N—H...O(hydrox­yl) hydrogen bonds in the crystal, which results in supra­molecular layers lying parallel to (100).

3-Hy­droxy-4-phenyl-1-(prop-2-en-1-yl)-2,3,4,5-tetra­hydro-1H-1,5-benzodiazepin-2-one

The asymmetric unit of the title compound, C₁₈H₁₈N₂O₂, contains three independent mol­ecules. In each, the seven-membered diazepine ring adopts a boat conformation with the hy­droxy-substituted C atom at the prow and fused-ring C atoms at the stern. In the crystal, the mol­ecules are linked by O—H...O and N—H...O hydrogen bonds. The allyl group of one mol­ecule is equally disordered over two positions.

Ethyl 2-(2-amino-5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7-yl)acetate

The nine-membered fused-ring of the title compound, C₁₀H₁₃N₅O₂, is approximately planar [maximum deviation = 0.012 (1) Å]; the bond angle at the methylene C atom is 111.33 (10)°. In the crystal, the amino group forms hydrogen bonds to the N atoms of the triazole rings of adjacent mol­ecules, generating a ribbon running along the a axis.

5-Bromo-1-(prop-2-en-1-yl)-2,3-dihydro-1H-indole-2,3-dione

In the title compound, C₁₁H₈BrNO₂, the nine-membered fused-ring is nearly planar [maximum deviation = 0.022 (2) Å] and the allyl group is arched over the nine-membered fused-ring at a dihedral angle of 89.2 (1)°. Weak inter­molecular C—H...O hydrogen bonding is present in the crystal structure.

3-{2-[(3-{(E)-2-[4-(Dimethyl­amino)­phen­yl]ethen­yl}quinoxalin-2-yl)­oxy]eth­yl}-1,3-oxazolidin-2-one monohydrate

In the title compound, C₂₃H₂₄N₄O₃·H₂O, the 1,3-oxazoline ring is nearly planar [maximum deviation = 0.059 (2) Å] and its mean plane is twisted by 30.12 (8)° with respect to the quinoxaline fused-ring system; the benzene ring is nearly coplanar with the quinoxaline fused-ring system [dihedral angle = 2.52 (2)°]. The water mol­ecule of crystallization is hydrogen-bond donor to an N atom of the quinoxaline ring system as well as an O atom of the oxazolinone unit, the two hydrogen bonds generating a chain running along the c axis.