Three-dimensional study of poly(lactic co-glycolic acid) micro-porous microspheres using hard X-ray nano-tomography

The Beijing Synchrotron Radiation Facility transmission X-ray microscope reveals the internal three-dimensional microstructure and functional parameters of poly(lactic co-glycolic acid) microspheres.

Double-focusing mixing jet for XFEL study of chemical kinetics

A novel method for time-resolved study of chemical kinetics using a windowless mixing jet at an X-ray free-electron laser (XFEL) is described and demonstrated. The short mixing time gives a time resolution of about 250 µs; the design introduces controllable delays after the initiation of a chemical reaction, allowing the possibility for detection of transient structures by an XFEL beam pulse. Applications may include time-resolved enzyme-substrate imaging or protein folding.