Pressure-induced high-density amorphous ice in protein crystals

High-density amorphous ice is shown to occur in high-pressure cryocooled protein crystallization solution and protein crystals, supporting a proposed mechanism for high-pressure cryocooling effects.

High hydrostatic pressure small-angle X-ray scattering cell for protein solution studies featuring diamond windows and disposable sample cells

A user-friendly high-pressure cell for synchrotron small-angle X-ray scattering studies of protein solutions is described. Disposable inner sample cells facilitate sample isolation, minimization and handling.