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J. Appl. Cryst. (2008). 41, 1-7
https://doi.org/10.1107/S0021889807048820

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Pressure-induced high-density amorphous ice in protein crystals

C. U. Kim, Y.-F. Chen, M. W. Tate and S. M. Gruner

High-density amorphous ice is shown to occur in high-pressure cryocooled protein crystallization solution and protein crystals, supporting a proposed mechanism for high-pressure cryocooling effects.

Keywords: high-pressure cryocooling; high-density amorphous ice; protein crystallization.

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