The structure of S100A12 in a hexameric form and its proposed role in receptor signalling

The structure of a hexameric form of S100A12, a member of the S100 family of proteins, has been solved at 2.7 Å resolution. The results suggest a functional significance for the hexamer.

Atomic resolution structures of ribonuclease A at six pH values

Six structures of bovine pancreatic ribonuclease at six pH values have been refined and analyzed. A comparative analysis of the six models and some biological implications are discussed.

Atomic resolution data reveal flexibility in the structure of RNase Sa

The structure of recombinant RNase Sa from 1.0 Å spacing synchrotron data collected at cryogenic temperature shows two alternative conformations of the main chain in two loops which contain active-site residues. This feature was not observed in the structure refined against room-temperature data at 1.2 Å resolution.

The structures of Micrococcus lysodeikticus catalase, its ferryl intermediate (compound II) and NADPH complex

The crystal structure of the bacterial catalase from M. lysodeikticus has been refined at 0.88 Å using the gene-derived sequence, revealing the active site with unprecedented accuracy. In addition, the structures of the ferryl intermediate of the catalase (compound II) at 1.96 Å resolution and the catalase complex with NADPH at 1.83 Å resolution have been determined.