Crystal structure of methyl 6-meth­oxy-11-(4-meth­oxy­phen­yl)-16-methyl-14-phenyl-8,12-dioxa-14,15-di­aza­tetra­cyclo­[8.7.0.0^2,7.0^13,17]hepta­deca-2(7),3,5,13(17),15-penta­ene-10-carboxyl­ate

In the title compound, the pyran and pyrone rings adopt slightly distorted half-chair and envelope conformations, respectively. In the crystal, C—H...O and π–π inter­actions connect the mol­ecules, forming double layers that stack along the c-axis direction.

Methyl 3′-benzyl-4′-(2,4-di­chloro­phen­yl)-1′-methyl-2-oxo-1-propyl­spiro­[indoline-3,2′-pyrrolidine]-3′-carboxy­l­ate

In the title compound, C₃₀H₃₀Cl₂N₂O₃, the indole ring system is roughly planar, with a maximum deviation of 0.1039 (18) Å for the carbonyl C atom, and makes a dihedral angle of 86.61 (9)° with the mean plane of the pyrrolidine ring. This spiro pyrrolidine ring adopts an envelope conformation with the N atom at the flap position. The pyrrole ring of the indole ring system adopts a twisted conformation on the C—C(=O) bond. The mol­ecular structure is stabilized by an intra­molecular C—H...O hydrogen bond, which generates an S(6) ring motif, and a π–π inter­action [centroid–centroid distance = 3.6577 (12) Å] involving the 2,4-di­chloro­phenyl ring and the benzyl ring. In the crystal, mol­ecules are linked via C—H...O hydrogen bonds, forming C(9) chains running parallel to [10-1].

Methyl 1-phenyl-3-p-tolyl-1,9b-di­hydro-3H-chromeno[4,3-c]isoxazole-3a(4H)-carboxyl­ate

In the title compound, C₂₅H₂₃NO₄, the pyran ring of the chroman moiety has an envelope conformation with the methyl­ene C atom as the flap. The isoxazole ring has a twist conformation on the O—C bond. The dihedral angle between their mean planes is 57.87 (9)°. The attached phenyl and benzene rings are twisted away from its mean plane by 56.19 (10) and 50.57 (10)°, respectively. These two rings are normal to each other, subtending a dihedral angle of 89.2 (1)°. In the crystal, there are no classical hydrogen bonds; the mol­ecules are linked via C—H...π inter­actions, forming a two-dimensional network lying parallel to (10-1).

Methyl 4′-(3-bromo­phen­yl)-3′-(2,5-di­methyl­benz­yl)-1′-methyl-2-oxo­spiro­[indo­line-3,2′-pyrrolidine]-3′-carboxyl­ate

In the title compound, C₂₉H₂₉BrN₂O₃, the indole ring system is essentially planar (r.m.s. deviation = 0.079 Å) and makes a dihedral angle of 85.23 (10)° with the mean plane of the 4-methyl­pyrrolidine ring. This ring adopts an envelope conformation with the N atom at the flap. The pyrrolidine ring of the indole ring system adopts a twisted conformation on the C—C(=O) bond. The mol­ecular structure is stabilized by an intra­molecular C—H...O hydrogen bond, which generates an S(6) ring motif. In the crystal, mol­ecules are linked via pairs of C—H...O hydrogen bonds, forming inversion dimers with an R₂²(14) ring motif. These dimers are further linked by N—H...O and C—H...O hydrogen bonds, forming two-dimensional networks lying parallel to (10-1).

Methyl 3′-benzyl-4′-(2,4-di­chloro­phen­yl)-1′-methyl-2-oxo­spiro­[indoline-3,2′-pyrrolidine]-3′-carboxyl­ate

In the title compound, C₂₇H₂₄Cl₂N₂O₃, the indole ring system is essentially planar, with a maximum deviation of 0.082 (2) Å for the carbonyl C atom. It makes a dihedral angle of 88.53 (6)° with the mean plane of the 4-methyl­pyrrolidine ring, which adopts an envelope conformation with the N atom at the flap position. The mol­ecular structure is stabilized by intra­molecular C—H...O hydrogen bonds, which generate S(6) and S(7) ring motifs, and an intra­molecular π–π inter­action involving the benzyl and di­chloro-substituted benzene rings [centroid–centroid distance = 3.6291 (11) Å]. In the crystal, mol­ecules are linked via N—H...O hydrogen bonds, forming C(7) chains running parallel to [10-1].

Methyl 3′-(2,5-di­methyl­benz­yl)-1′-methyl-2-oxo-4′-phenyl­spiro­[indoline-3,2′-pyrrolidine]-3′-carboxyl­ate chloro­form monosolvate

In the title solvate, C₂₉H₃₀N₂O₃·CHCl₃, the dihedral angle between the indole ring system (r.m.s. deviation = 0.050 Å) and the 4-methyl­pyrrolidine ring is 88.88 (8)°. The latter ring adopts an envelope conformation with the N atom as the flap. Its mean plane makes dihedral angles of 86.94 (11) and 42.08 (9)° with the phenyl and di­methyl­benzene rings, respectively. The mol­ecular conformation is stabilized by intra­molecular C—H...O hydrogen bonds, which generate S(6) and S(9) ring motifs. The chloro­form solvent mol­ecule is linked to the organic mol­ecule by a C—H...O hydrogen bond involving the carbonyl O atom of the carboxyl­ate group. In the crystal, mol­ecules are linked via bifurcated N—H...(N,O) and C—H...O hydrogen bonds, forming chains propagating along [001].

Methyl (E)-3-(2-formyl­phen­oxy)acrylate

In the title compound, C₁₁H₁₀O₄, the methyl acrylate sub­stituent adopts an extended E conformation with all torsion angles close to 180°. The conformation of the keto group with respect to the olefinic double bond is typically S-trans. In the crystal, mol­ecules are linked via pairs of C—H...O hydrogen bonds, forming inversion dimers with an R₂²(8) graph-set motif. The dimers are further linked via C—H...O hydrogen bonds, forming chains along [001], which enclose R₃²(16) graph-set ring motifs. The keto group O atomaccepts two C—H...O interactions.