journal menu
organic compounds
Open 
access
access
In the title compound, C24H26FN3O, the cyclohexane ring adopts a chair conformation; the propyl substituent is in an equatorial orientation and the bond-angle sum at the C atom bonded to the carbohydrazide N atom is 360.0°. The dihedral angle between the 1H-indole ring system and the phenyl ring is 82.77 (13)°. A weak intramolecular C—H
π contact occurs. In the crystal, pairs of molecules related by a crystallographic twofold axis are linked by bifurcated N—H(O,N) hydrogen bonds; a C—HO interaction occurs between the same pair. The dimers are linked by C—HF and C—Hπ interactions, generating a three-dimensional network.
π contact occurs. In the crystal, pairs of molecules related by a crystallographic twofold axis are linked by bifurcated N—H(O,N) hydrogen bonds; a C—HO interaction occurs between the same pair. The dimers are linked by C—HF and C—Hπ interactions, generating a three-dimensional network.organic compoundsOpen access
access
The title compound, C22H22FN3O, crystallized with two independent molecules (A and B) in the asymmetric unit; these are linked by a pair of N—HO hydrogen bonds, forming a pseudo-centrosymmetric dimer with an R22(10) motif. In addition, a number of C—Hπ interactions are also observed. The 1H-indole ring systems in molecules A and B are essentially planar [maximum deviations of 0.019 (2) and 0.014 (2) Å, respectively] and make dihedral angles of 77.64 (10) and 69.50 (9)°, respectively, with thephenyl rings.
O hydrogen bonds, forming a pseudo-centrosymmetric dimer with an R22(10) motif. In addition, a number of C—Hπ interactions are also observed. The 1H-indole ring systems in molecules A and B are essentially planar [maximum deviations of 0.019 (2) and 0.014 (2) Å, respectively] and make dihedral angles of 77.64 (10) and 69.50 (9)°, respectively, with thephenyl rings.organic compoundsOpen access
access
In the title compound, C24H24FN3O2S, the 1,3-thiazolidine ring adopts an envelope conformation with the S atom as the flap, while the cyclohexane ring is in a chair conformation. In the crystal, molecules are linked by N—HO and C—HF hydrogen bonds, forming a three-dimensional network. The unit cell contains six voids of 57 Å3, but the residual electron density (highest peak = 0.23 e Å−3 and deepest hole = −0.19 e Å−3) in the difference Fourier map suggests no solvent molecule occupies this void.
O and C—HF hydrogen bonds, forming a three-dimensional network. The unit cell contains six voids of 57 Å3, but the residual electron density (highest peak = 0.23 e Å−3 and deepest hole = −0.19 e Å−3) in the difference Fourier map suggests no solvent molecule occupies this void.organic compoundsOpen access
access
The title compound, C23H24FN3O, crystallizes with two independent molecules (I and II) in the asymmetric unit. These pairs of molecules are linked to each other as N—HO dimers with an R22(10) motif. Furthermore, the crystal structure also exhibits C—Hπ interactions. The atoms of the ethyl group in molecule I are disordered over two sites with an occupancy ratio of 0.817 (6):0.183 (6).
O dimers with an R22(10) motif. Furthermore, the crystal structure also exhibits C—Hπ interactions. The atoms of the ethyl group in molecule I are disordered over two sites with an occupancy ratio of 0.817 (6):0.183 (6).
