N-Acetyl-5-chloro-3-nitro-L-tyrosine ethyl ester

The title compound, C₁₃H₁₅ClN₂O₆, was synthesized by hypochlorous acid-mediated chlorination of N-acetyl-3-nitro-L-tyrosine ethyl ester. The OH group forms an intra­molecular O—H...O hydrogen bond to the nitro group and the N—H group forms an inter­molecular N—H...O hydrogen bonds to an amide O atom, linking the mol­ecules into chains along [100]. The crystal studied was a non-merohedral twin, with a 0.907 (4):0.093 (4) domain ratio.