N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)-4,4′′-difluoro-5′-hy­droxy-1,1′:3′,1′′-terphenyl-4′-carboxamide

The asymmetric unit of the title compound, C₂₇H₁₆F₂N₂O₄, consists of two crystallographically independent mol­ecules (A and B). In mol­ecule B, the isoindoline-1,3-dione ring system is disordered over two set of sites with a site-occupancy ratio of 0.658 (12):0.342 (12). In mol­ecule A, the fluoro-substituted benzene rings make dihedral angles of 18.36 (8) and 46.37 (8)° with the central benzene ring, whereas the corresponding angles are 40.90 (8) and 52.89 (9)° in mol­ecule B. The isoindoline ring system in mol­ecule A and the major and minor components of the disordered isoindoline ring system in mol­ecule B make dihedral angles of 58.50 (4), 54.13 (16) and 70.01 (28) °, respectively, with their attached benzene rings, linked through the amide group. An intra­molecular O—H...O hydrogen bond generates an S(6) ring in each mol­ecule. In the crystal, mol­ecules are linked by N—H...O, C—H...F and C—H...O hydrogen bonds into sheets lying parallel to the bc plane. The crystal studied was a non-merohedral twin with a refined twin component ratio of 0.9316 (8):0.0684 (8).

1-[3-(4-Fluoro­phen­yl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl]ethanone

In the title compound, C₁₇H₁₅FN₂O, the pyrazoline ring adopts a flattened envelope conformation. The dihedral angle between the fluoro-substituted benzene ring and the phenyl ring is 69.20 (5)°. In the crystal, a pair of C—H...O hydrogen bonds link neighbouring mol­ecules, forming an inversion dimer. The crystal structure is further consolidated by C—H...π inter­actions and by a π–π inter­action with a centroid–centroid distance of 3.7379 (6) Å.

1-[5-(4-Bromo­phen­yl)-3-(4-fluoro­phen­yl)-4,5-dihydro-1H-pyrazol-1-yl]butan-1-one

In the title compound, C₁₉H₁₈BrFN₂O, the benzene rings form dihedral angles of 5.38 (7) and 85.48 (7)° with the mean plane of the 4,5-dihydro-1H-pyrazole ring (r.m.s. deviation = 0.0849 Å), which approximates to an envelope conformation with the –CH₂– group as the flap. The dihedral angle between the benzene rings is 82.86 (7)°. In the crystal, C—H...F and C—H...O hydrogen bonds link the mol­ecules to form inversion dimers and together these generate chains along [011]. The crystal packing also features C—H...π inter­actions.

N-(2-Bromo­phen­yl)-2-(naphthalen-1-yl)acetamide

In the title compound, C₁₈H₁₄BrNO, the naphthalene ring system [maximum deviation = 0.015 (3) Å] forms a dihedral angle of 67.70 (10)° with the benzene ring. In the crystal, mol­ecules are linked by N—H...O hydrogen bonds into C(4) chains propagating in [100]. A C—H...O inter­action reinforces the chain connectivity, generating an R₂¹(6) loop.

(2E)-3-(2-Fluoro­phen­yl)-1-(4-fluoro­phen­yl)prop-2-en-1-one

In the title compouund, C₁₅H₁₀F₂O, the mol­ecule exists in an E conformation with respect to the C=C bond [1.3382 (16) Å]. The dihedral angle between the fluoro-substituted benzene rings is 6.80 (6)° and the whole mol­ecule is roughly planar (r.m.s. deviation for the non-H atoms = 0.069 Å). In the crystal, mol­ecules are linked by C—H...F and C—H...O inter­actions into sheets lying parallel to the bc plane.

2,2-Diphenyl-N-(2,4,5-trichloro­phen­yl)acetamide

The asymmetric unit of the title compound, C₂₀H₁₄Cl₃NO, consists of two independent mol­ecules. In one mol­ecule, the chlorinated benzene ring forms dihedral angles of 12.00 (9) and 77.04 (9)° with the phenyl rings. The dihedral angle between the phenyl rings is 80.37 (10)°. The corresponding dihedral angles for the other mol­ecule are 26.34 (10), 62.98 (10) and 88.47 (11)°, respectively. One of the mol­ecules features an intra­molecular C—H...O hydrogen bond, which forms an S(6) ring motif. In the crystal, mol­ecules are linked by N—H...O hydrogen bonds into [100] chains. The chains are further linked by C—H...O and C—H...Cl hydrogen bonds into a three-dimensional network.

N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-[4-(methyl­sulfan­yl)phen­yl]acetamide

In the title compound, C₂₀H₂₁N₃O₂S, the 2,3-dihydro-1H-pyrazole ring is nearly planar (r.m.s. deviation = 0.023 Å) and forms dihedral angles of 16.96 (6) and 38.93 (6)° with the benzene and phenyl rings, respectively. The dihedral angle between the benzene and phenyl rings is 55.54 (6)°. The mol­ecular conformation is consolidated by an intra­molecular C—H...O hydrogen bond, which forms an S(6) ring. In the crystal, inversion dimers linked by pairs of N—H...O_p (p = pyrazole) hydrogen bonds generate R₂²(10) loops. The dimers are linked by C—H...O hydrogen bonds into sheets lying parallel to (100).

2-(4-Bromo­phen­yl)-N-(2,6-dimethyl­phen­yl)acetamide

In the title compound, C₁₆H₁₆BrNO, the dihedral angle between the benzene rings is 69.8 (2)°. In the crystal, N—H...O hydrogen bonds link the mol­ecules into C(4) chains propagating in [100]. Adjacent mol­ecules in the chains are also linked by C—H...O inter­actions which, along with the N—H...O hydrogen bonds, generate R₂¹(6) loops.

2-(4-Chloro­phen­yl)-N-(1,3-thia­zol-2-yl)acetamide

In the title compound, C₁₁H₉ClN₂OS, the thia­zole ring is nearly planar (r.m.s. deviation = 0.003 Å) and forms a dihedral angle of 64.18 (7)° with the bezene ring. In the crystal, inversion dimers linked by pairs of N—H...N_t (t = thia­zole) hydrogen bonds generate R₂²(8) loops.

5-(4-Bromo­phen­yl)-3-(4-fluoro­phen­yl)-1-phenyl-4,5-dihydro-1H-pyrazole

In the title compound, C₂₁H₁₆BrFN₂, the fluoro-substituted benzene ring is disordered over two orientations about the C—F bond and the C—C bond between the benzene and pyrazole groups with a site-occupancy ratio of 0.516 (8):0.484 (8). The central pyrazole ring [maximum deviation = 0.035 (3) Å] makes dihedral angles of 22.4 (2), 11.0 (2), 77.19 (16) and 7.44 (17)° with the two disorder components of the benzene ring, the bromo-substituted benzene ring and the phenyl ring, respectively. In the crystal, mol­ecules are linked into a layer parallel to the bc plane through C—H...π inter­actions.

1-(6-Chloro-1,3-benzothia­zol-2-yl)-2-[1-(4-meth­oxy­phen­yl)ethyl­idene]hydrazine

The asymmetric unit of the title compound, C₁₆H₁₄ClN₃OS, contains two independent mol­ecules (A and B) linked into dimers via N—H...N hydrogen bonds. The 1,3-benzothia­zol-2-yl ring system and the benzene ring form dihedral angles of 17.08 (8) and 8.63 (7)° in mol­ecules A and B, respectively.

(2E)-3-[4-(Benz­yloxy)phen­yl]-1-(pyridin-3-yl)prop-2-en-1-one

The title compound, C₂₁H₁₇NO₂, exists in an E conformation with respect to the C=C bond. The pyridine ring forms dihedral angles of 5.57 (7) and 82.30 (9)°, respectively, with the central benzene ring and the terminal phenyl ring. The dihedral angle between the benzene and phenyl rings is 87.69 (8)°. No significant inter­molecular inter­actions are observed.

Ethyl 6-(4-meth­oxy­phen­yl)-2-oxo-4-phenyl­cyclo­hex-3-ene­carboxyl­ate

The asymmetric unit of the title compound, C₂₂H₂₂O₄, consists of two independent mol­ecules (A and B). The cyclo­hexene rings adopt slightly distorted sofa conformations in both mol­ecules. The dihedral angles between the benzene rings are 74.16 (13) and 71.85 (13)° in mol­ecules A and B, respectively. In the crystal, weak C—H...O hydrogen bonds link the mol­ecules into a ribbon-like structure along the b axis. Weak C—H...π inter­actions are also observed.