4-(4-Bromo­phen­yl)-1-(2,6-difluoro­benz­yl)-3-(3,4,5-trimeth­oxy­phen­yl)-1H-1,2,4-triazole-5(4H)-thione

In the title compound, C₂₄H₂₀BrF₂N₃O₃S, the triazole ring (r.m.s. deviation = 0.0107 Å) makes dihedral angles of 28.18 (14), 63.76 (14) and 77.01 (18)°, respectively, with the trimeth­oxy-, bromo-, and difluoro-substituted benzene rings. The C atoms of the meta meth­oxy groups are roughly coplanar with their ring [displacements = −0.289 (4) and 0.083 (7) Å], whereas the C atom of the para group is displaced [1.117 (3) Å]. In the crystal, inversion dimers linked by two pairs of C—H...O hydrogen bonds occur. The ring motif of the two hydrogen bonds to their symmetry-generated O-atom acceptors is R₂²(8).

2-[(E)-4-Diethyl­amino-2-hy­droxy­benzyl­idene]hydrazinecarboxamide

Two mol­ecules make up the asymmetric unit of the title compound, C₁₂H₁₈N₄O₂, and both feature an intra­molecular O—H...N hydrogen bond, which generates an S(6) ring. The diethyl­amino group of one of the mol­ecules is disordered over two sets of sites in a 0.59 (2):0.41 (2) ratio. In the crystal, N—H...O hydrogen bonds link the mol­ecules into sheets lying parallel to the ac plane and C—H...π inter­actions are also observed.

Ethyl 1-(2,4-dichloro­benz­yl)-4-oxo-7-trifluoro­meth­yl-1,4-dihydro­quinoline-3-carboxyl­ate

In the title compound, C₂₀H₁₄Cl₂F₃NO₃, the trifluromethyl group is disordered over two sets of sites in a 0.784 (10):0.216 (10) ratio. The quinoline ring system is essentially planar with a maximum deviation of 0.058 (2) Å for the N atom and forms dihedral angles of 89.23 (11) and 8.13 (17)°, respectively with the mean planes of the benzene ring and the carboxyl­ate group. In the crystal, pairs of weak C—H...O and C—H...F hydrogen bonds link mol­ecules into centrosymmetric dimers. The crystal structure is further stabilized by weak π–π [centroid–centroid distance = 3.624 (2) Å] inter­actions.

2-(4-Fluoro­phen­yl)-2-oxoethyl 2-methoxy­benzoate

In the title compound, C₁₆H₁₃FO₄, the aromatic rings enclose an angle of 73.68 (6)°. In the crystal, C—H...O and C—H...F contacts connect the mol­ecules into a three-dimensional network. The shortest inter­centroid distance between two aromatic π-systems is 3.6679 (7) Å and is apparent between the fluorinated phenyl groups.

Diethyl 2-{[2-(trifluoro­meth­yl)anil­ino]methyl­idene}propane­dioate

The title compound, C₁₅H₁₆F₃NO₄, is an N-substituted derivative of ortho-trifluoro­methyl­aniline featuring a twofold Michael system. The least-squares planes defined by the atoms of the phenyl ring and the atoms of the Michael system enclose an angle of 15.52 (5)°. Apart from classical intra­molecular N—H...O and N—H...F hydrogen bonds, inter­molecular C—H...O contacts are observed, the latter connecting the mol­ecules into chains along [110]. The shortest inter­centroid distance between two aromatic systems is 3.6875 (9) Å.

(2E)-1-(2,4-Dichloro­phen­yl)-3-[3-(4-nitro­phen­yl)-1-phenyl-1H-pyrazol-4-yl]prop-2-en-1-one

In the title compound, C₂₄H₁₅Cl₂N₃O₃, the C=C double bond is E configured. The 1-phenyl-1H-pyrazole moiety is roughly planar (r.m.s. deviation of all fitted non-H atoms = 0.0780 Å), but the mean planes of the two components are inclined at an angle of 9.95 (7)°. The mean plane defined by the non-H atoms of the 1H-pyrazole ring encloses angles of 9.95 (7), 24.54 (6) and 43.02 (6)° with the mean planes of the different benzene rings. In the crystal, C—H...O contacts are present and result in the formation of a double-layer two-dimensional network lying parallel to (110). The shortest inter­centroid distance between two aromatic systems is 3.5455 (7) Å and is apparent between two pyrazole systems. Further π–π inter­actions are manifest between a pair of 4-nitro­phenyl rings [centroid-to-centroid distance = 3.6443 (7) Å] and a pair of 2,4-dichloro­phenyl rings [centroid-to-centroid distance = 3.7797 (7) Å].

Methyl 2-[(2-methyl­phen­oxy)meth­yl]benzoate

In the title methyl­benzoate compound, C₁₆H₁₆O₃, the mol­ecule is essentially planar (r.m.s. of all fitted non-H atoms = 0.0370 Å); the dihedral angle between the phenyl rings is 2.30 (7)°. Apart from a C—H...π inter­action, no marked inter­molecular contacts are obvious.

2-(8-Bromo­imidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethyl­amino-2-hy­droxy­benzyl­idene]acetohydrazide dihydrate

In the title compound, C₂₀H₂₂BrN₅O₂·2H₂O, the Schiff base mol­ecule exists in an E conformation with respect to the acyclic C=N bond. An S(6) ring motif is formed via an intra­molecular O—H...N hydrogen bond. The dihedral angle between the imidazo[1,2-a]pyridine system and the benzene ring is 84.62 (5)°. In the crystal, N—H...O, O—H...O, O—H...N, C—H...O and C—H...Br hydrogen bonds link the mol­ecules into a three-dimensional network. The crystal packing is further stabilized by C—H...π and π–π inter­actions [centroid–centroid distance = 3.5365 (7) Å].

Diethyl 2,6-dimethyl-4-(5-phenyl-1H-pyrazol-4-yl)-1,4-dihydro­pyridine-3,5-dicarboxyl­ate

In the title compound, C₂₂H₂₅N₃O₄, the dihydro­pyridine ring adopts a flattened boat conformation. The pyrazole ring makes a dihedral angle of 29.04 (5)° with the benzene ring. The mol­ecular structure is stabilized by an intra­molecular C—H...O hydrogen bond which generates an S(9) ring motif. In the crystal, mol­ecules are linked via N—H...O and C—H...N hydrogen bonds into a two-dimensional network parallel to the ab plane. The crystal structure is further consolidated by weak C—H...π inter­actions.

Dimethyl 2,6-dimethyl-4-(3-phenyl-1H-pyrazol-4-yl)-1,4-dihydro­pyridine-3,5-dicarboxyl­ate

In the title compound, C₂₀H₂₁N₃O₄, the 1,4-dihydro­pyridine ring adopts a boat conformation. An intra­molecular C—H...O hydrogen bond generates an S(6) ring motif. The pyrazole ring makes dihedral angles of 87.81 (7) and 45.09 (7)° with the mean plane of the 1,4-dihydro­pyridine ring and the phenyl ring, respectively. In the crystal, mol­ecules are linked by N—H...N, N—H...O and C—H...O hydrogen bonds into a three-dimensional network.

4-[3-(Biphenyl-4-yl)-1-phenyl-4,5-di­hydro-1H-pyrazol-5-yl]-3-(4-meth­oxy­phen­yl)-1-phenyl-1H-pyrazole dioxane monosolvate

In the title compound, C₃₇H₃₀N₄O·C₄H₈O₂, the dihedral angle between the pyrazole and dihydro­pyrazole rings is 74.09 (10)°. In the crystal, the components are linked into centrosymmetric tetra­mers (two main mol­ecules and two solvent mol­ecules) by C—H...O hydrogen bonds. C—H...π and π–π [shortest centroid-centroid separation = 3.6546 (9) Å] inter­actions are also observed.

Diethyl 4-[5-(4-chloro­phen­yl)-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate

In the title compound, C₂₂H₂₄ClN₃O₄, intra­molecular C—H...O and C—H...N hydrogen bonds form S(9) and S(7) ring motifs, respectively. The 1,4-dihydro­pyridine ring adopts a flattened boat conformation. The benzene ring makes a dihedral angle of 33.36 (6)° with the pyrazole ring. In the crystal, pairs of N—H...N hydrogen bonds link the mol­ecules into inversion dimers. The dimers are stacked in column along the a axis through N—H...O and C—H...N hydrogen bonds. The crystal packing also features C—H...π inter­actions involving the pyrazole ring.

2-(4-Bromo­phen­yl)-2-oxoethyl anthracene-9-carboxyl­ate

In the title compound, C₂₃H₁₅BrO₃, the anthracene ring system is essentially planar [maximum deviation = 0.29 (2) Å] and makes a dihedral angle of 5.74 (8)° with the mean plane of the bromo-substituted benzene ring. An intra­molecular C—H...O hydrogen bond generates an S(9) ring motif. In the crystal, mol­ecules are linked by C—H...O inter­actions, forming a two-dimensional network parallel to the ac plane. π–π stacking inter­actions are observed between benzene rings [centroid–centroid distances = 3.5949 (14) and 3.5960 (13) Å].

Dimethyl 4-[3-(4-meth­oxy­phen­yl)-1-phenyl-1H-pyrazol-4-yl]-2,6-dimethyl-1,4-dihydro­pyridine-3,5-dicarboxyl­ate dihydrate

In the title compound, C₂₇H₂₇N₃O₅·2H₂O, the dihydro­pyridine ring adopts a flattened boat conformation. The central pyrazole ring is essentially planar [maximum deviation of 0.003 (1) Å] and makes dihedral angles of 50.42 (6) and 26.44 (6)° with the benzene rings. In the crystal, mol­ecules are linked via N—H...O, O—H...O, O—H...N and C—H...O hydrogen bonds into two-dimensional networks parallel to the bc plane. The crystal structure is further consolidated by weak C—H...π inter­actions.

(2E)-3-(6-Meth­oxy­naphthalen-2-yl)-1-[4-(methyl­sulfan­yl)phen­yl]prop-2-en-1-one

The asymmetric unit of the title compound, C₂₁H₁₈O₂S, consists of two crystallographically independent mol­ecules (A and B). The mol­ecules exist in a trans conformation with respect to the central C=C bond. The naphthalene ring system makes dihedral angles of 51.62 (12) (mol­ecule A) and 52.69 (12)° (mol­ecule B) with the benzene ring. In mol­ecule A, the prop-2-en-1-one group forms dihedral angles of 22.84 (15) and 29.02 (12)° with the adjacent naphthalene ring system and benzene ring, respectively, whereas the corresponding angles are 30.04 (12) and 23.33 (12)° in mol­ecule B. In the crystal, mol­ecules are linked by inter­molecular C—H...O hydrogen bonds into head-to-tail chains along the a axis. The crystal packing also features C—H...π inter­actions. The crystal studied was a pseudo-merohedral twin with twin law (100 0-10 00-1) and a refined component ratio of 0.6103 (16):0.3897 (16).

1-[(3-Benz­yloxy-2-nitro­phen­oxy)meth­yl]benzene

The asymmetric unit of the title compound, C₂₀H₁₇NO₄, consists of two crystallographically independent mol­ecules. In one of the mol­ecules, the central benzene ring forms dihedral angles of 2.26 (6) and 58.68 (6)° with the terminal benzene rings and the dihedral angle between the terminal benzene rings is 56.45 (6)°. The corresponding values for the other mol­ecule are 35.17 (6), 70.97 (6) and 69.62 (6)°, respectively. In the crystal, an inversion dimer linked by a pair of C—H...O hydrogen bonds occurs for one of the unique mol­ecules. C—H...π and π–π [centroid–centroid distances = 3.7113 (8) and 3.7216 (7) Å] inter­actions link the components into a three-dimensional network.

2-Cyclo­pentyl­idenehydrazine­carboxamide

The asymmetric unit of the title compound, C₆H₁₁N₃O, consists of two independent mol­ecules in which the cyclo­pentane rings adopt envelope conformations with CH₂ grouping as the flap and the semicarbazone groups are essentially planar, with maximums deviation of 0.0311 (12) and 0.0285 (12) Å. In the crystal, N—H...O, N—H...N and C—H...O hydrogen bonds link the mol­ecules to form sheets lying parallel to the ab plane.

Ethyl 4-{[1-(2,4-dichloro­benz­yl)-1H-1,2,3-triazol-4-yl]meth­oxy}-8-(trifluoro­meth­yl)quinoline-3-carboxyl­ate

In the title compound, C₂₃H₁₇Cl₂F₃N₄O₃, the triazole ring makes dihedral angles of 50.27 (6) and 82.78 (7)° with the quinoline ring system and the dichloro-substituted benzene ring. The dihedral angle between the quinoline and dichloro-substituted benzene rings is 38.17 (4)°. In the crystal, mol­ecules are linked via C—H...N, C—H...F and C—H...O hydrogen bonds into a three-dimensional network. The crystal is further consolidated by C—H...π contacts to the triazole ring and inversion-related π–π inter­actions between the benzene and pyridine rings of quinoline systems [centroid–centroid distance = 3.7037 (7) Å].

1-(4-Bromo­phen­yl)-2-(2-chloro­phen­oxy)ethanone

In the title compound, C₁₄H₁₀BrClO₂, a twofold halogenated derivative of phenyl­ated phenyl­oxyethanone, the least-squares planes defined by the C atoms of the aromatic rings subtend an angle of 71.31 (17)°. In the crystal, C—H...O contacts connect the mol­ecules into chains along the b-axis direction.

1,5-Dibromo-2,4-dimeth­oxy­benzene

In the title compound, C₈H₈Br₂O₂, all non-H atoms lie essentially in a common plane (r.m.s deviation of all fitted non-H atoms = 0.0330 Å). In the crystal, weak C—H...O hydrogen bonds connect the mol­ecules, forming chains which extend along the b-axis direction.