Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae

H. M. Greenblatt, T. C. Otto, M. G. Kirkpatrick, E. Kovaleva, S. Brown, G. Buchman, D. M. Cerasoli and J. L. Sussman

Large quantities of recombinant human carboxylesterase 1 have been produced in an economical whole insect larvae system. The crystal structure of this enzyme is essentially identical to that produced by cell culture techniques.

Keywords: human carboxylesterase 1; whole-insect expression system; Trichoplusia ni.

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