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In the title compound, C39H36N2O4S, the piperidine ring adopts a twisted half-chair conformation. In the pyrrolo­thia­zole fused-ring system, the pyrrole ring adopts an envelope conformation (with the C atom bound to the thia­zole ring being the flap atom) and the thia­zole ring also exhibits an envelope conformation (with the N atom bound to the pyrrole ring as the flap). The mol­ecular structure features a weak intra­molecular C—H...O inter­action. In the crystal, a C—H...O inter­action forms a linear chain along the diagonal of the ac plane, generating a C(14) graph-set motif. A weak C—H...π inter­action also occurs.
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