research papers
The crystal structure of the FERM domain of merlin has been solved by molecular replacement and refined to 1.8 Å resolution. Missense mutations causing neurofibromatosis type 2 are examined.
research papers
Studies of a number of Glu→Ala single and multiple mutants of RhoGDI show that such mutations may be generally useful to enhance protein crystallizability. One of the mutants yielded data to 1.2 Å resolution, showing that surface mutants can be used to dramatically improve the resolution of X-ray data.