A high-pressure polymorph of chlorpropamide formed on hydrostatic compression of the α-form in saturated ethanol solution

The crystal structure of a high-pressure monoclinic polymorph (P2₁11) of chlorpropamide has been determined. It is formed at ∼ 2.8 GPa on hydrostatic compression of the orthorhombic stable α-polymorph (P2₁2₁2₁) in saturated ethanol solution.

A high-pressure single-crystal to single-crystal phase transition in DL-alaninium semi-oxalate mono­hydrate with switching-over hydrogen bonds

The first example of a single-crystal diffraction study of a high-pressure phase transition in a crystalline amino acid salt hydrate is reported. The transition is accompanied by pronounced discontinuities in the cell parameters and volume versus pressure, although no radical changes in the molecular packing are induced.