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In the title co-crystal, C12H11Br2N3O·C4H5NO2, the naphthyridine derivative and the pyrrolidine-2,5-dione mol­ecules have crystallographic mirror-plane symmetry with all non-H atoms, except the Br atom, located on the mirror plane. In the crystal, N—H...N, N—H...O and C—H...O hydrogen bonds link the mol­ecules into heterodimers. These dimers are further linked into a one-dimensional structure along [010] by weak C—Br...O inter­actions [Br...O = 3.028 (5) Å and C—Br...O = 158.52 (4)°].

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In the title adduct, C11H11N3O·C2H4O2, all non-H atoms of the acetamide mol­ecule are roughly coplanar, with an r.m.s. deviation of 0.0720 Å. The dihedral angle between the ring plane and the acetamide group is 8.5 (2)°. In the crystal, O—H...N and N—H...O hydrogen bonds link the acetamide and acetic acid mol­ecules.
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