organic compounds
The title compound {systematic name: (+)-(S)-3-[5-cyano-2-(4-fluorophenyl)-1,3-dihydroisobenzofuran-2yl]propanaminium oxalate oxalic acid 0.325-hydrate}, 2C20H22FN2O+·C2O42−·C2H2O4·0.325H2O, is a molecular salt of the N-protonated escitalopram cation. As well as charge-balancing oxalate dianions, neutral molecules of oxalic acid are present. The component species interact by way of N—HO and short O—HO hydrogen bonds, resulting in supramolecular chains.
organic compounds
In the structure of the title salt [systematic name: 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-aminium 2,4,6-trinitrophenolate] of a tricyclic antidepressant, C20H24N+·C6H2N3O7−, the dimethylaminopropyl subunit possesses a classical static conformational disorder. The central cycloheptadiene ring adopts a bent conformation that is intermediate between boat and chair forms, leading to a butterfly shape for the hetero-tricyclic moiety. In a complementary fashion, donors from amitriptyline and acceptors from picrate form intermolecular C—HO hydrogen bonds and N—HO salt bridges. These hydrogen bonds cluster amitriptyline and picrate ions into a closed R44(36) hetero-tetramer, whereas intermolecular C—Hπ interactions between amitriptyline ions cluster them into homo-dimers. Significant π–π stacking interactions are also observed between aromatic rings of amitriptyline and picrate, and these, combined with the C—Hπ interactions, associate molecules into linear arrays along the [11] direction.